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Combined Therapy of Oncolytic Adenovirus and Temozolomide Enhances Lung Cancer Virotherapy In Vitro and In Vivo

Oncolytic adenoviruses (OAds) are very promising for the treatment of lung cancer. However, OAd-based monotherapeutics have not been effective during clinical trials. Therefore, the effectiveness of virotherapy must be enhanced by combining OAds with other therapies. In this study, the therapeutic p...

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Bibliographic Details
Published in:Virology
Main Authors: Gomez-Gutierrez, Jorge G., Nitz, Jonathan, Sharma, Rajesh, Wechman, Stephen L., Riedinger, Eric, Martinez-Jaramillo, Elvis, Zhou, Heshan Sam, McMasters, Kelly M.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679495/
https://ncbi.nlm.nih.gov/pubmed/26561948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.10.019
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