Temozolomide renders murine cancer cells susceptible to oncolytic adenovirus replication and oncolysis

The preclinical evaluation of oncolytic adenoviruses (OAds) has been limited to cancer xenograft mouse models because OAds replicate poorly in murine cancer cells. The alkylating agent temozolomide (TMZ) has been shown to enhance oncolytic virotherapy in human cancer cells; therefore, we investigate...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Garza-Morales, Rodolfo, Yaddanapudi, Kavitha, Perez-Hernandez, Rigoberto, Riedinger, Eric, McMasters, Kelly M., Shirwan, Haval, Yolcu, Esma, Montes de Oca-Luna, Roberto, Gomez-Gutierrez, Jorge G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836815/
https://ncbi.nlm.nih.gov/pubmed/29252087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1416274
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