Temozolomide renders murine cancer cells susceptible to oncolytic adenovirus replication and oncolysis

The preclinical evaluation of oncolytic adenoviruses (OAds) has been limited to cancer xenograft mouse models because OAds replicate poorly in murine cancer cells. The alkylating agent temozolomide (TMZ) has been shown to enhance oncolytic virotherapy in human cancer cells; therefore, we investigate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Biol Ther
Egile Nagusiak: Garza-Morales, Rodolfo, Yaddanapudi, Kavitha, Perez-Hernandez, Rigoberto, Riedinger, Eric, McMasters, Kelly M., Shirwan, Haval, Yolcu, Esma, Montes de Oca-Luna, Roberto, Gomez-Gutierrez, Jorge G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2018
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836815/
https://ncbi.nlm.nih.gov/pubmed/29252087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1416274
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