Adenovirus lacking E1b efficiently induces cytopathic effect in HPV-16-positive murine cancer cells via virus replication and apoptosis

Conditionally replicative adenoviruses (CRAds) replicate poorly in murine cancer cells; however, E1b-deleted CRAds may replicate effectively in HPV16-E6/E7-positive murine cancer cells (TC-1). The HPV16 E7 open reading frame encodes functions analogous to these deleted adenovirus E1 proteins. In thi...

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發表在:Cancer Invest
Main Authors: Martinez-Jaramillo, Elvis, Garza-Morales, Rodolfo, Wechman, Stephen L, de Oca-Luna, Roberto Montes, Saucedo-Cardenas, Odila, Shirwan, Haval, Yolcu, Esma, McMasters, Kelly M., Gomez-Gutierrez, Jorge G.
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088374/
https://ncbi.nlm.nih.gov/pubmed/29388837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07357907.2018.1430812
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