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Human NK cell lytic granules and regulation of their exocytosis

Natural killer (NK) cells form a subset of lymphocytes that play a key role in immuno-surveillance and host defense against cancer and viral infections. They recognize stressed cells through a variety of germline-encoded activating cell surface receptors and utilize their cytotoxic ability to elimin...

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Hlavní autoři: Krzewski, Konrad, Coligan, John E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494098/
https://ncbi.nlm.nih.gov/pubmed/23162553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00335
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