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Fluctuation Dynamics Analysis of gp120 Envelope Protein Reveals a Topologically Based Communication Network
HIV infection is initiated by binding of the viral glycoprotein gp120, to the cellular receptor CD4. Upon CD4 binding, gp120 undergoes conformational change, permitting binding to the chemokine receptor. Crystal structures of gp120 ternary complex reveal the CD4 bound conformation of gp120. We repor...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494097/ https://ncbi.nlm.nih.gov/pubmed/20718047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22816 |
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