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An Interaction between DNA Polymerase and Helicase Is Essential for the High Processivity of the Bacteriophage T7 Replisome

Synthesis of the leading DNA strand requires the coordinated activity of DNA polymerase and DNA helicase, whereas synthesis of the lagging strand involves interactions of these proteins with DNA primase. We present the first structural model of a bacteriophage T7 DNA helicase-DNA polymerase complex...

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Detaylı Bibliyografya
Asıl Yazarlar: Kulczyk, Arkadiusz W., Akabayov, Barak, Lee, Seung-Joo, Bostina, Mihnea, Berkowitz, Steven A., Richardson, Charles C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493946/
https://ncbi.nlm.nih.gov/pubmed/22977246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410647
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