IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

Chronic mucosal inflammation and tissue damage predisposes patients to the development of colorectal cancer (CRC)(1). This association could be explained by the hypothesis that the same factors and pathways important for wound healing also promote tumorigenesis. A sensor of tissue damage should indu...

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Detalhes bibliográficos
Main Authors: Huber, Samuel, Gagliani, Nicola, Zenewicz, Lauren A., Huber, Francis J., Bosurgi, Lidia, Hu, Bo, Hedl, Matija, Zhang, Wei, O’Connor, William, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Booth, Carmen J., Cho, Judy H., Ouyang, Wenjun, Abraham, Clara, Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493690/
https://ncbi.nlm.nih.gov/pubmed/23075849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11535
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