Galactosylated IgG1 links FcγRIIB and Dectin-1 to block complement-mediated inflammation

Complement is an ancient danger sensing system playing critical roles in host defense, immune surveillance and homeostasis(1). C5a and its G-Protein-coupled receptor mediate many of the pro-inflammatory properties of complement(2). Despite its critical role in allergic asthma(3), autoimmune arthriti...

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Bibliografische gegevens
Hoofdauteurs: Karsten, Christian M., Pandey, Manoj K., Figge, Julia, Kilchenstein, Regina, Taylor, Philip R., Rosas, Marcela, McDonald, Jacqueline U., Orr, Selinda J., Berger, Markus, Petzold, Dominique, Blanchard, Veroniqué, Winkler, André, Hess, Constanze, Reid, Delyth M., Majoul, Irina V., Strait, Richard T., Harris, Nathaniel L., Köhl, Gabriele, Wex, Eva, Ludwig, Ralf, Zillikens, Detlef, Nimmerjahn, Falk, Finkelman, Fred D., Brown, Gordon D., Ehlers, Marc, Köhl, Jörg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492054/
https://ncbi.nlm.nih.gov/pubmed/22922409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2862
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