Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo

Maintenance of immunological tolerance is crucial to prevent development of autoimmune disease. The production of autoantibodies is a hallmark of many autoimmune diseases and studies in mouse model systems suggest that inhibitory signaling molecules may be important checkpoints of humoral tolerance....

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Main Authors: Baerenwaldt, Anne, Lux, Anja, Danzer, Heike, Spriewald, Bernd M., Ullrich, Evelyn, Heidkamp, Gordon, Dudziak, Diana, Nimmerjahn, Falk
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219118/
https://ncbi.nlm.nih.gov/pubmed/22065769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111810108
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