Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo

Maintenance of immunological tolerance is crucial to prevent development of autoimmune disease. The production of autoantibodies is a hallmark of many autoimmune diseases and studies in mouse model systems suggest that inhibitory signaling molecules may be important checkpoints of humoral tolerance....

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Autors principals: Baerenwaldt, Anne, Lux, Anja, Danzer, Heike, Spriewald, Bernd M., Ullrich, Evelyn, Heidkamp, Gordon, Dudziak, Diana, Nimmerjahn, Falk
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219118/
https://ncbi.nlm.nih.gov/pubmed/22065769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111810108
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