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Lubiprostone Activates CFTR, but not ClC-2, via the Prostaglandin Receptor (EP(4))
The goal of this study was to determine the mechanism of lubiprostone activation of epithelial chloride transport. Lubiprostone is a bicyclic fatty acid approved for the treatment of constipation [1]. There is uncertainty, however, as to how lubiprostone increases epithelial chloride transport. Dire...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489164/ https://ncbi.nlm.nih.gov/pubmed/22960173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.08.097 |
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