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Cysteine Accessibility in ClC-0 Supports Conservation of the ClC Intracellular Vestibule

ClC chloride channels, which are ubiquitously expressed in mammals, have a unique double-barreled structure, in which each monomer forms its own pore. Identification of pore-lining elements is important for understanding the conduction properties and unusual gating mechanisms of these channels. Stru...

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Détails bibliographiques
Auteurs principaux: Engh, Anita M., Maduke, Merritt
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234078/
https://ncbi.nlm.nih.gov/pubmed/15897295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509258
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