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The Role of a Conserved Lysine in Chloride- and Voltage-dependent ClC-0 Fast Gating
ClC-0 is a chloride channel whose gating is sensitive to voltage, chloride, and pH. In a previous publication, we showed that the K149C mutation causes a +70-mV shift in the voltage dependence of ClC-0 fast gating. In this paper we analyze the effects of a series of mutations at K149 on the voltage...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151651/ https://ncbi.nlm.nih.gov/pubmed/17846165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709760 |
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