Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon

Background and purpose: Lubiprostone (Amitiza), a possible ClC-2 channel opener derived from prostaglandin E(1) and indicated for the treatment of constipation, increases chloride ion transport and fluid secretion into the intestinal lumen. As lubiprostone may also directly modulate gastrointestinal...

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Detaylı Bibliyografya
Asıl Yazarlar: Bassil, A K, Borman, R A, Jarvie, E M, McArthur-Wilson, R J, Thangiah, R, Sung, E Z H, Lee, K, Sanger, G J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2008
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438971/
https://ncbi.nlm.nih.gov/pubmed/18332851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.84
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