Downregulation of prostaglandin E receptor subtype EP(3) during colon cancer development

Background and aims: Involvement of prostaglandin E(2) (PGE(2)) receptors EP(1), EP(2), and EP(4) in the formation of aberrant crypt foci (ACF) and/or intestinal polyps has been suggested. In contrast, EP(3) appears to have no influence on the early stages of colon carcinogenesis. In the present stu...

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Autori principali: Shoji, Y, Takahashi, M, Kitamura, T, Watanabe, K, Kawamori, T, Maruyama, T, Sugimoto, Y, Negishi, M, Narumiya, S, Sugimura, T, Wakabayashi, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2004 by Gut 2004
Soggetti:
Colorectal Cancer
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774140/
https://ncbi.nlm.nih.gov/pubmed/15247185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.028787
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