Susceptibility to bystander DNA damage is influenced by replication and transcriptional activity

Direct cellular DNA damage may lead to genome destabilization in unexposed, bystander, cells sharing the same milieu with directly damaged cells by means of the bystander effect. One proposed mechanism involves double strand break (DSB) formation in S phase cells at sites of single strand lesions in...

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Main Authors: Dickey, Jennifer S., Baird, Brandon J., Redon, Christophe E., Avdoshina, Valeriya, Palchik, Guillermo, Wu, Junfang, Kondratyev, Alexei, Bonner, William M., Martin, Olga A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488239/
https://ncbi.nlm.nih.gov/pubmed/22941641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks795
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