Susceptibility to bystander DNA damage is influenced by replication and transcriptional activity

Direct cellular DNA damage may lead to genome destabilization in unexposed, bystander, cells sharing the same milieu with directly damaged cells by means of the bystander effect. One proposed mechanism involves double strand break (DSB) formation in S phase cells at sites of single strand lesions in...

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Detalhes bibliográficos
Main Authors: Dickey, Jennifer S., Baird, Brandon J., Redon, Christophe E., Avdoshina, Valeriya, Palchik, Guillermo, Wu, Junfang, Kondratyev, Alexei, Bonner, William M., Martin, Olga A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488239/
https://ncbi.nlm.nih.gov/pubmed/22941641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks795
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