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The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication

The GINS complex, originally discovered in Saccharomyces cerevisiae and Xenopus laevis, binds to DNA replication origins shortly before the onset of S phase and travels with the replication forks after initiation. In this study we present a detailed characterization of the human GINS (hGINS) homolog...

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Autores principales: Aparicio, Tomás, Guillou, Emmanuelle, Coloma, Javier, Montoya, Guillermo, Méndez, Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673421/
https://ncbi.nlm.nih.gov/pubmed/19223333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp065
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