Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutants.
We have examined mutant lines of Chinese hamster ovary cells that have increased resistance to the antimicrotubule drug Colcemid. Analysis of the functional properties of purified microtubule protein indicates that increased tolerance to the drug in vivo is reflected in altered properties of microtu...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1981
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348812/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6946501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.9.5638 |
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