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Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutants.

We have examined mutant lines of Chinese hamster ovary cells that have increased resistance to the antimicrotubule drug Colcemid. Analysis of the functional properties of purified microtubule protein indicates that increased tolerance to the drug in vivo is reflected in altered properties of microtu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Keates, R A, Sarangi, F, Ling, V
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1981
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6946501/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.9.5638
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