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Revertants of a Chinese Hamster Ovary Cell Mutant with an Altered β-Tubulin: Evidence that the Altered Tubulin Confers Both Colcemid Resistance and Temperature Sensitivity on the Cell

We recently described the isolation of a mutant Chinese hamster ovary cell (Cmd 4) resistant to the cytotoxic effects of colcemid (Cabral et al., Cell 20:29-36, 1980). This mutant carries an altered β-tubulin but still grows normally at 37°C. In the present study we found that Cmd 4 is temperature s...

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Publicat a:Mol Cell Biol
Autors principals: Cabral, Fernando, Abraham, Irene, Gottesman, Michael M.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1982
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14582168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.6.720
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