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Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the molecule

Using flow cytometry, fluorescent microscopy, and examination of receptor glycosylation status, we demonstrate that an entire KIR locus (KIR2DS3) – previously assumed to be surface expressed – appears to have little appreciable surface expression in transfected cells. This phenotype was noted for re...

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Autores principales: VandenBussche, Christopher James, Mulrooney, Tiernan Joseph, Frazier, William Robinson, Dakshanamurthy, Sivanesan, Hurley, Carolyn Katovich
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487464/
https://ncbi.nlm.nih.gov/pubmed/19005473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2008.91
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