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Extracellular domain alterations impact surface expression of stimulatory natural killer cell receptor KIR2DS5
In the human killer cell immunoglobulin-like receptors, KIR2DL2, and KIR2DL3, a triad of amino acids in the D1 domain interact to stabilize protein structure. Substitution of any one of these residues caused significant loss of cell surface expression. Although KIR2DS4 and KIR2DS5, two homologous re...
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| Pubblicato in: | Immunogenetics |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5848465/ https://ncbi.nlm.nih.gov/pubmed/18682925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-008-0322-2 |
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