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Allelic Variation in KIR2DL3 Generates a KIR2DL2-like Receptor with Increased Binding to Its HLA-C Ligand()

Although extensive homology exists between their extracellular domains, natural killer cell inhibitory receptors KIR2DL2*001 and KIR2DL3*001 have previously been shown to differ substantially in their HLA-C binding avidity. To explore the largely uncharacterized impact of allelic diversity, the most...

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Detalhes bibliográficos
Main Authors: Frazier, William R., Steiner, Noriko, Hou, Lihua, Dakshanamurthy, Sivanesan, Hurley, Carolyn Katovich
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679298/
https://ncbi.nlm.nih.gov/pubmed/23686481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300464
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