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Allelic Variation of Killer Cell Immunoglobulin-Like Receptor 2DS5 Impacts Glycosylation Altering Cell Surface Expression Levels

Natural killer cell stimulatory receptor gene, KIR2DS5, is polymorphic. While KIR2DS5*002 is most frequently observed, other alleles have also been found. The proteins encoded by these alleles (KIR2DS5*002 - *009) are expressed at varying levels on the surface of NKL and Jurkat transfectants. Gel el...

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Detalhes bibliográficos
Main Authors: Steiner, Noriko K., Dakshanamurthy, Sivanesan, Nguyen, Nicholas, Hurley, Carolyn K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924325/
https://ncbi.nlm.nih.gov/pubmed/24269691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2013.11.012
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