Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases. Most of the antineoplastic drugs are metabolized to be detoxified, and some of them to be activated. Genetic polymorphisms...

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Bibliographic Details
Main Authors: Roco, Ángela, Quiñones, Luis, Agúndez, José A. G., García-Martín, Elena, Squicciarini, Valentina, Miranda, Carla, Garay, Joselyn, Farfán, Nancy, Saavedra, Iván, Cáceres, Dante, Ibarra, Carol, Varela, Nelson
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2012
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487109/
https://ncbi.nlm.nih.gov/pubmed/23130019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00229
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