Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases. Most of the antineoplastic drugs are metabolized to be detoxified, and some of them to be activated. Genetic polymorphisms...

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Hlavní autoři: Roco, Ángela, Quiñones, Luis, Agúndez, José A. G., García-Martín, Elena, Squicciarini, Valentina, Miranda, Carla, Garay, Joselyn, Farfán, Nancy, Saavedra, Iván, Cáceres, Dante, Ibarra, Carol, Varela, Nelson
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2012
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487109/
https://ncbi.nlm.nih.gov/pubmed/23130019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00229
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