Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases. Most of the antineoplastic drugs are metabolized to be detoxified, and some of them to be activated. Genetic polymorphisms...

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Autors principals: Roco, Ángela, Quiñones, Luis, Agúndez, José A. G., García-Martín, Elena, Squicciarini, Valentina, Miranda, Carla, Garay, Joselyn, Farfán, Nancy, Saavedra, Iván, Cáceres, Dante, Ibarra, Carol, Varela, Nelson
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2012
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487109/
https://ncbi.nlm.nih.gov/pubmed/23130019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00229
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