Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases. Most of the antineoplastic drugs are metabolized to be detoxified, and some of them to be activated. Genetic polymorphisms...

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Main Authors: Roco, Ángela, Quiñones, Luis, Agúndez, José A. G., García-Martín, Elena, Squicciarini, Valentina, Miranda, Carla, Garay, Joselyn, Farfán, Nancy, Saavedra, Iván, Cáceres, Dante, Ibarra, Carol, Varela, Nelson
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2012
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487109/
https://ncbi.nlm.nih.gov/pubmed/23130019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00229
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