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Oral cancer susceptibility associated with the CYP1A1 and GSTM1 genotypes in Chilean individuals

Polycyclic aromatic hydrocarbons (PAHs) contained in tobacco smoke acquire carcinogenicity following their activation by xenobiotic-metabolizing enzymes to highly reactive metabolites. The cytochrome P4501A1 (CYP1A1) enzyme is central to the metabolic activation of these PAHs, and GSTM1 is the main...

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Bibliographic Details
Main Authors: CORDERO, KARINA, ESPINOZA, IRIS, CACERES, DANTE, ROCO, ANGELA, MIRANDA, CARLA, SQUICCIARINI, VALENTINA, SANTANDER, PAULA, LEE, KUEN, SAAVEDRA, IVÁN, QUIÑONES, LUIS
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436421/
https://ncbi.nlm.nih.gov/pubmed/22966341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol_00000097
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