Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Mitochondria from diverse organisms are capable of transporting large amounts of Ca(2+) via a ruthenium-red-sensitive, membrane-potential-dependent mechanism called the uniporter(1–4). Although the uniporter’s biophysical properties have been studied extensively, its molecular composition remains el...

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Detalhes bibliográficos
Main Authors: Baughman, Joshua M., Perocchi, Fabiana, Girgis, Hany S., Plovanich, Molly, Belcher-Timme, Casey A., Sancak, Yasemin, Bao, X. Robert, Strittmatter, Laura, Goldberger, Olga, Bogorad, Roman L., Koteliansky, Victor, Mootha, Vamsi K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486726/
https://ncbi.nlm.nih.gov/pubmed/21685886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10234
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