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Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
Mitochondria from diverse organisms are capable of transporting large amounts of Ca(2+) via a ruthenium-red-sensitive, membrane-potential-dependent mechanism called the uniporter(1–4). Although the uniporter’s biophysical properties have been studied extensively, its molecular composition remains el...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486726/ https://ncbi.nlm.nih.gov/pubmed/21685886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10234 |
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