Global Effect of Interleukin-10 on the Transcriptional Profile Induced by Neisseria meningitidis in Human Monocytes

In meningococcal septic shock, the dominant inducer of inflammation is lipopolysaccharide (LPS) in the outer membrane of Neisseria meningitidis, while interleukin-10 (IL-10) is the principal anti-inflammatory cytokine. We have used microarrays and Ingenuity Pathway Analysis to study the global effec...

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Main Authors: Gopinathan, Unni, Øvstebø, Reidun, Olstad, Ole Kristoffer, Brusletto, Berit, Dalsbotten Aass, Hans Christian, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486056/
https://ncbi.nlm.nih.gov/pubmed/22966040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-12
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