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Global Effect of Interleukin-10 on the Transcriptional Profile Induced by Neisseria meningitidis in Human Monocytes

In meningococcal septic shock, the dominant inducer of inflammation is lipopolysaccharide (LPS) in the outer membrane of Neisseria meningitidis, while interleukin-10 (IL-10) is the principal anti-inflammatory cytokine. We have used microarrays and Ingenuity Pathway Analysis to study the global effec...

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Bibliografski detalji
Glavni autori: Gopinathan, Unni, Øvstebø, Reidun, Olstad, Ole Kristoffer, Brusletto, Berit, Dalsbotten Aass, Hans Christian, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486056/
https://ncbi.nlm.nih.gov/pubmed/22966040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-12
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