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Global Effect of Interleukin-10 on the Transcriptional Profile Induced by Neisseria meningitidis in Human Monocytes

In meningococcal septic shock, the dominant inducer of inflammation is lipopolysaccharide (LPS) in the outer membrane of Neisseria meningitidis, while interleukin-10 (IL-10) is the principal anti-inflammatory cytokine. We have used microarrays and Ingenuity Pathway Analysis to study the global effec...

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Bibliografiske detaljer
Main Authors: Gopinathan, Unni, Øvstebø, Reidun, Olstad, Ole Kristoffer, Brusletto, Berit, Dalsbotten Aass, Hans Christian, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486056/
https://ncbi.nlm.nih.gov/pubmed/22966040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-12
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