Global Effect of Interleukin-10 on the Transcriptional Profile Induced by Neisseria meningitidis in Human Monocytes

In meningococcal septic shock, the dominant inducer of inflammation is lipopolysaccharide (LPS) in the outer membrane of Neisseria meningitidis, while interleukin-10 (IL-10) is the principal anti-inflammatory cytokine. We have used microarrays and Ingenuity Pathway Analysis to study the global effec...

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Hlavní autoři: Gopinathan, Unni, Øvstebø, Reidun, Olstad, Ole Kristoffer, Brusletto, Berit, Dalsbotten Aass, Hans Christian, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486056/
https://ncbi.nlm.nih.gov/pubmed/22966040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-12
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