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Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10

BACKGROUND: Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used Gene Set Enrichment Analysis (GSEA) and Ingenuity Pathway Analysis (IPA) to analyze previously generated DNA microarray data from hu...

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Bibliografiske detaljer
Udgivet i:BMC Immunol
Main Authors: Gopinathan, Unni, Øvstebø, Reidun, Brusletto, Berit Sletbakk, Olstad, Ole Kristoffer, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659018/
https://ncbi.nlm.nih.gov/pubmed/29078758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-017-0229-5
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