Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10

BACKGROUND: Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used Gene Set Enrichment Analysis (GSEA) and Ingenuity Pathway Analysis (IPA) to analyze previously generated DNA microarray data from hu...

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Vydáno v:BMC Immunol
Hlavní autoři: Gopinathan, Unni, Øvstebø, Reidun, Brusletto, Berit Sletbakk, Olstad, Ole Kristoffer, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659018/
https://ncbi.nlm.nih.gov/pubmed/29078758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-017-0229-5
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