Regional Variation in Aortic AT1b Receptor mRNA Abundance Is Associated with Contractility but Unrelated to Atherosclerosis and Aortic Aneurysms

BACKGROUND: Angiotensin II (AngII), the main bioactive peptide of the renin angiotensin system, exerts most of its biological actions through stimulation of AngII type 1 (AT1) receptors. This receptor is expressed as 2 structurally similar subtypes in rodents, termed AT1a and AT1b. Although AT1a rec...

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Autores principales: Poduri, Aruna, Owens, A. Phillip, Howatt, Deborah A., Moorleghen, Jessica J., Balakrishnan, Anju, Cassis, Lisa A., Daugherty, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485205/
https://ncbi.nlm.nih.gov/pubmed/23119030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048462
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