Mucosal Immunization with Live Attenuated Francisella novicida U112ΔiglB Protects against Pulmonary F. tularensis SCHU S4 in the Fischer 344 Rat Model

The need for an efficacious vaccine against Francisella tularensis is a consequence of its low infectious dose and high mortality rate if left untreated. This study sought to characterize a live attenuated subspecies novicida-based vaccine strain (U112ΔiglB) in an established second rodent model of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Signarovitz, Aimee L., Ray, Heather J., Yu, Jieh-Juen, Guentzel, M. N., Chambers, James P., Klose, Karl E., Arulanandam, Bernard P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484155/
https://ncbi.nlm.nih.gov/pubmed/23118885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047639
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados