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Vaccination with a Defined Francisella tularensis subsp. novicida Pathogenicity Island Mutant (ΔiglB) Induces Protective Immunity Against Homotypic and Heterotypic Challenge
Francisella tularensis, an intracellular Gram-negative bacterium, is the causative agent of tularemia and a potential bioweapon. Currently, there is no licensed vaccine against this organism. We have characterized the efficacy of a defined F. tularensis subsp. novicida mutant (ΔiglB) as a live atten...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752818/ https://ncbi.nlm.nih.gov/pubmed/19651173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.07.034 |
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