Live Attenuated Francisella novicida Vaccine Protects against Francisella tularensis Pulmonary Challenge in Rats and Non-human Primates

Francisella tularensis causes the disease tularemia. Human pulmonary exposure to the most virulent form, F. tularensis subsp. tularensis (Ftt), leads to high morbidity and mortality, resulting in this bacterium being classified as a potential biothreat agent. However, a closely-related species, F. n...

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Bibliografiske detaljer
Main Authors: Chu, Ping, Cunningham, Aimee L., Yu, Jieh-Juen, Nguyen, Jesse Q., Barker, Jeffrey R., Lyons, C. Rick, Wilder, Julie, Valderas, Michelle, Sherwood, Robert L., Arulanandam, Bernard P., Klose, Karl E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207810/
https://ncbi.nlm.nih.gov/pubmed/25340543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004439
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