Live Attenuated Francisella novicida Vaccine Protects against Francisella tularensis Pulmonary Challenge in Rats and Non-human Primates

Francisella tularensis causes the disease tularemia. Human pulmonary exposure to the most virulent form, F. tularensis subsp. tularensis (Ftt), leads to high morbidity and mortality, resulting in this bacterium being classified as a potential biothreat agent. However, a closely-related species, F. n...

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Detalhes bibliográficos
Main Authors: Chu, Ping, Cunningham, Aimee L., Yu, Jieh-Juen, Nguyen, Jesse Q., Barker, Jeffrey R., Lyons, C. Rick, Wilder, Julie, Valderas, Michelle, Sherwood, Robert L., Arulanandam, Bernard P., Klose, Karl E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207810/
https://ncbi.nlm.nih.gov/pubmed/25340543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004439
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