Longitudinal Modeling of Cognitive Aging and the TOMM40 Effect

BACKGROUND: TOMM40 (translocase of the outer mitochondrial membrane pore subunit) is in linkage disequilibrium with apolipoprotein E (APOE). APOE e4 is linked to long (L; 21–29 T residues) poly-T variants within intron 6 of TOMM40 while APOE e3 can be associated with either with a short (S; <21 T...

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Autors principals: Caselli, Richard J., Dueck, Amylou C., Huentelman, Matthew J., Lutz, Michael W., Saunders, Ann M., Reiman, Eric M., Roses, Allen D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483561/
https://ncbi.nlm.nih.gov/pubmed/23102119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2011.11.006
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