Loading...
A novel approach to the discovery of small molecule ligands of CDK2
In an attempt to identify novel small molecule ligands of CDK2 with potential as allosteric inhibitors, we devised a robust and cost-effective fluorescence-based high-throughput screening assay. The assay is based on the specific interaction of CDK2 with the extrinsic fluorophore 8-anilino-1-naphtha...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483082/ https://ncbi.nlm.nih.gov/pubmed/22893598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200316 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|