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Discovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3)

Increasing evidence suggests key roles for members of the mammalian Sterile20-like (MST) family of kinases in many aspects of biology. MST3 is a member of the STRIPAK complex, the deregulation of which has recently been associated with cancer cell migration and metastasis. Targeting MST3 with small-...

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Библиографические подробности
Опубликовано в: :ChemMedChem
Главные авторы: Olesen, Sanne H., Zhu, Jin-Yi, Martin, Mathew P., Schönbrunn, Ernst
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771544/
https://ncbi.nlm.nih.gov/pubmed/27135311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600115
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