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Plant-Produced Asialo-Erythropoietin Restores Pancreatic Beta-Cell Function by Suppressing Mammalian Sterile-20-like Kinase (MST1) and Caspase-3 Activation

Pancreatic beta-cell death adversely contributes to the progression of both type I and II diabetes by undermining beta-cell mass and subsequently diminishing endogenous insulin production. Therapeutics to impede or even reverse the apoptosis and dysfunction of beta-cells are urgently needed. Asialo-...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Arthur, Elena, Kittur, Farooqahmed S., Lin, Yuan, Hung, Chiu-Yueh, Sane, David C., Xie, Jiahua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395651/
https://ncbi.nlm.nih.gov/pubmed/28469576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00208
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