Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1.

Mst1 is a ubiquitously expressed serine-threonine kinase, homologous to the budding yeast Ste20, whose physiological regulation and cellular function are unknown. In this paper we show that Mst1 is specifically cleaved by a caspase 3-like activity during apoptosis induced by either cross-linking CD9...

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Detalhes bibliográficos
Main Authors: Graves, J D, Gotoh, Y, Draves, K E, Ambrose, D, Han, D K, Wright, M, Chernoff, J, Clark, E A, Krebs, E G
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170567/
https://ncbi.nlm.nih.gov/pubmed/9545236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.8.2224
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