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MAPPING MOLECULAR FLEXIBILITY OF PROTEINS WITH SITE DIRECTED SPIN LABELING: A CASE STUDY OF MYOGLOBIN()

Site directed spin labeling (SDSL) has potential for mapping protein flexibility under physiological conditions. The purpose of the present study was to explore this potential using 38 singly spin-labeled mutants of myoglobin distributed throughout the sequence. Correlation of the EPR spectra with p...

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Библиографические подробности
Главные авторы: López, Carlos J., Oga, Shirley, Hubbell, Wayne L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483079/
https://ncbi.nlm.nih.gov/pubmed/22809279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3005686
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