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MAPPING MOLECULAR FLEXIBILITY OF PROTEINS WITH SITE DIRECTED SPIN LABELING: A CASE STUDY OF MYOGLOBIN()

Site directed spin labeling (SDSL) has potential for mapping protein flexibility under physiological conditions. The purpose of the present study was to explore this potential using 38 singly spin-labeled mutants of myoglobin distributed throughout the sequence. Correlation of the EPR spectra with p...

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Bibliografske podrobnosti
Main Authors: López, Carlos J., Oga, Shirley, Hubbell, Wayne L.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483079/
https://ncbi.nlm.nih.gov/pubmed/22809279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3005686
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