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Determination of the Orientation of T4 Lysozyme Vectorially Bound to a Planar-Supported Lipid Bilayer Using Site-Directed Spin Labeling

Site-directed spin labeling is used to investigate the structure of adsorbed T4 lysozyme (T4L). A monolayer of T4L is prepared by tethering the protein selectively via a His-tag to the chelating headgroups (NTA Ni) of a planar quartz-supported lipid bilayer. This results in a vectorially oriented en...

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Autores principales: Jacobsen, Kerstin, Oga, Shirley, Hubbell, Wayne L., Risse, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305663/
https://ncbi.nlm.nih.gov/pubmed/15778448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.059725
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